Accentia Biopharmaceuticals
Advanced Immunotherapeutics
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Expert Cell Culture Contract Manufacturing Services and a Diverse Line of Systems for Your Biologic Production Needs
Over two decades of proven experience in biomanufacturing...
The National Cell Culture Division (a Biovest Company) provides expert customized, cell culture services (contract manufacturing) for customers in the public and private sectors.
Located in Minneapolis, Minnesota, our 33,000 sq ft facility includes laboratory, manufacturing, warehousing, and contract cell culture space shared by a team of research and biomanufacturing professionals at the Master's and Doctoral levels in multiple fields of medicines and life sciences.
Cell Culture Contract Manufacturing Services Include:
- Cell-line Development
- Purification: GMP and non-GMP
- Media Assessment
- Regulation: Advisory Services
- Cell-line Optimization
- Aseptic Fill
- Process Development and Optimization
- Production: GMP and non-GMP
- Technology Transfer
We have decades of experience in the production of over 1700 cell lines. We routinely produce numerous common cell lines, such as HeLa, CHO, 293, BHK, and hybridomas.
Our large-scale production services include: Mammalian Cells (Suspension Culture at 1-400 liters per day or Anchorage Dependent Culture at 1-200 roller bottles per batch); Purified Monoclonal Antibodies (10 mg to 100 grams); Non-Hybridoma Cell Secreted Proteins; and Conditioned Media.
We will adapt your cell line or custom protocol to large-scale production in order to deliver your cells in the quantity and frequency you need, while also offering Cell Banking and Storage Services.
- Innovative Line of Automated Bioreactors
- Superior High Cell Density Production
- Minimizes Costs / Increases Efficiency
- Research, Clinical and Commercial Scalability
- Disposable Features for Speed & Ease-of-Use
- Ideal for MAbs and Personalized Medicines
Case Studies:
Why Should I Choose Advanced Hollow Fiber?
The Accusyst™ Line of Advanced Hollow Fiber Bioreactors:
An extremely compact, self-contained, completely enclosed, fully-automated advanced hollow fiber bioreactor system that delivers rapid, efficient scale-up of patient-derived cells.
Exceptional performance based on advanced hollow fiber technology, ideally suited for high-density cell culture in the production of monoclonal antibodies and other therapeutic proteins.
Composed of disposable elements for all product contact components to maximize speed and manufacturing flexibility.
Used in the Production of Biovest's Anti-Cancer Vaccine, BiovaxID®